Nordic Tests ApS
Chembio DPP Syphilis Screen & Confirm Test (20 pcs)
Chembio DPP Syphilis Screen & Confirm Test (20 pcs)
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DPP Syphilis Screen & Confirm Test
The DPP Syphilis Screen & Confirm Test is a rapid, qualitative test for the simultaneous detection of treponemal and non-treponemal antibodies in human fingerstick blood, venous whole blood, serum or plasma. The test is intended for professional in vitro diagnostic use and is suitable for point-of-care testing.
The test is designed for both screening and confirmatory assessment of syphilis in a single assay. This provides a practical solution in clinical settings where rapid results and a simple workflow are important.
Benefits
- Simultaneous detection of treponemal and non-treponemal antibodies
- Suitable for screening and confirmatory assessment in a single test
- Rapid test for point-of-care use
- Can be used with multiple sample types
- Developed for professional use
Use
The DPP Syphilis Screen & Confirm Test is a single-use test for the simultaneous qualitative detection of antibodies to non-treponemal antigens and Treponema pallidum.
The test can be used with the following sample types:
- Finger-prick blood
- Venous whole blood
- Serum
- Plasma
The test is intended for professional use as a point-of-care test to aid in screening and confirmation of syphilis infection.
Specifications
| Test type | Immunochromatographic rapid test with DPP® technology |
| Analyte | Treponemal and non-treponemal antibodies |
| Sample material | Finger-prick blood, venous whole blood, serum or plasma |
| Result time | Rapid point-of-care assay |
| Storage | 2–30 °C |
| Use | Professional in vitro diagnostic use |
| Intended use | Screening and confirmation of syphilis |
| Manufacturer | Chembio Diagnostics, Inc. |
Interpretation of Results
- Non-reactive: Only the control line is visible, with no reactive test lines.
- Treponemal reactive: Control line and treponemal test line are visible.
- Non-treponemal reactive: Control line and non-treponemal test line are visible.
- Double reactive: Control line and both test lines are visible.
- Invalid: If the control line does not appear, the test is invalid.
A reactive result must always be interpreted in conjunction with clinical findings and any additional laboratory diagnostics. The test is intended as an aid for screening and confirmation and should be used in accordance with current professional guidelines.
Package contents
- DPP Syphilis Screen & Confirm test cassettes
- Sample collection equipment
- Assay buffer / sample buffer
- Running buffer
- Instructions for use
Questions?
If you are unsure whether this test suits your needs, or have questions about how to use the test, you are always welcome to contact us.
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Product information
Product description
Chembio DPP® Syphilis Screen & Confirm – CE-marked dual rapid test
Chembio DPP® Syphilis Screen & Confirm represents a new standard in point-of-care diagnostics for syphilis. The test enables both screening and confirmation in the same cassette, as it separately measures treponemal (T) and non-treponemal (NT) antibodies. This provides a clearer indication of whether there is an active infection or a past syphilis infection and allows treatment decisions to be made quickly and close to the patient.
Function and method
The test is based on Chembio’s Dual Path Platform® (DPP®) lateral-flow technology. A small sample volume is applied to the sample well, followed by buffer. After approximately 15 minutes, two independent lines develop: the T line for treponemal antibodies and the NT line for non-treponemal antibodies. A control line confirms correct test performance.
Performance and accuracy
In large datasets with more than 1,600 serum samples, the T line showed high concordance with TP-PA (approx. 96.5% reactive and 95.5% non-reactive). The NT line had particularly high sensitivity at RPR titer levels of 1:8 or higher (almost 100%) and a specificity of around 98.6%. Independent studies have shown that use of the DPP® Micro Reader increases sensitivity, especially at low titers where visual interpretation may be less reliable.
Benefits
DPP® Syphilis Screen & Confirm combines two assays in one test, saving time, resources and often an additional clinic visit. It supports more precise and actionable decisions because it indicates whether an active infection is likely. The test is easy to perform, requires minimal training, and can be used in laboratories, clinics and outreach settings. It can also reduce overtreatment and unnecessary costs often associated with serial testing algorithms.
Intended use
The test is designed for professional use and is particularly relevant in STI clinics, infectious disease departments, antenatal programs and harm-reduction initiatives. It is useful in areas with a high prevalence of syphilis and in situations where rapid diagnosis and decision-making are crucial. In populations with many low titers, it is recommended to use the DPP® Micro Reader or supplement with laboratory testing, depending on local guidelines.
Ordering information
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